Description

Carotid Atherosclerotic Disease: Pathologic Basis for Treatment reviews the natural history of carotid atherosclerotic plaque and outlines different pathologic characteristics of asymptomatic and symptomatic carotid plaque with the intent to give a pathology-based rationale for assessment, risk stratification and decision-making therapeutic strategy of patients affected by carotid disease. Another section further illustrates - in a evidence based medicine format - the impact of carotid plaque imaging from high-resolution MRI to new Doppler imaging modalities and vasa vasorum detection to correctly assess plaque risk stratification. The new concept of a tailored stent for different plaque morphologies and usage of dedicated cerebral protection devices in presence of particular plaque features will be pointed up. The concluding section sheds light on future advancement in gene therapy and carotid arterial wall repair. This volume offers the reader all the basis necessary to shift from the old concept of 'when' to treat - based on simple luminal narrowing - to the new concept of 'who should be treated' - based on plaque and patient characteristics.

Description

This monograph covers all aspects of the roles that the haemostatic system and endothelial cells play in the pathogenesis and treatment of atherosclerotic cardiovascular disease (ASCVD) and its major clinical implications, including stroke, myocardial infarction, and peripheral vascular disease.;Providing complementary perspectives from international experts, Atherosclerotic Cardiovascular Disease, Haemostasis, and Endothelial Function offers in-depth discussions of: coagulation factors and endogenous coagulation inhibitors in ASCVD; the contribution of impaired fibrinolysis to the pathogenesis of ASCVD; the relationship of lipid abnormalities and hyperinsulinemia to altered coagulation and fibrinolysis; elevated plasma homocysteine; antiphospholipid antibodies and ASCVD; altered platelet activity in ASCVD; and vasoconstrictive and vasodilating factors derived from the endothelium in ASCVD.;With over 1700 literature citations and figures, this reference is intended for cardiologists, haematologists, physiologists epidemiologists, internists, and medical school students in these disciplines.

Description

Carotid atherosclerosis is a major and growing public health problem which frequently occurs concurrently with coronary artery disease. This book closely examines the benefits of current therapies (medical, surgical and interventional) providing a focussed, yet comprehensive review of atherosclerotic carotid disease. It includes a brief overview of carotid disease, followed by a detailed review of its medical management, various surgical studies and finishes with a look at recent advances in interventional techniques. This State of the Art book provides readers with an unparalleled opportunity to update themselves rapidly on advances in the field of carotid disease.

Description

The most common cause of premature death in the U.S. and in many of the world's countries is atherosclerotic cardiovascular disease, which includes coronary heart disease, peripheral vascular disease, and stroke. Most epidemiologic studies of risk factors for atherosclerosis have been conducted in adult populations, yet there is now clear evidence that the atherosclerotic process begins at a very early age. This book reviews recent findings that help physicians identify and manage children and adolescents who are at the highest risk for developing premature cardiovascular disease in later life. It reviews cholesterol levels, blood pressure levels, body size and tobacco use as risk factors for obesity, diabetes, coronary artery calcification and increased carotid artery intimal-medial thickness; it also discusses the measurement, familial aggregation, tracking and management of each of these risk factors.The book merges epidemiology and pathophysiology with descriptions of risk factors in childhood and adolescence and how they affect blood vessels and the heart. The organization of the book makes clear the most up-to-date clinical recommendations from the National High Blood Pressure Education Program, the National Cholesterol Education Program, the American Academy of Pediatrics and the American Heart Association, while also presenting the results of epidemiologic studies that support the clinical recommendations. This provides the reader with both the science and application of pediatric preventive cardiology. This book is for doctors and other health professionals who practice preventive cardiology in children, adolescents and young adults. It is for school nurses and school administrators who are committed to developing a healthful school environment with appropriate attention to school lunches and physical activity. For those who teach epidemiology and public health, it provides a complete discussion of pediatric atherosclerotic cardiovascular disease epidemiology. For medical historians, the book also offers an historical perspective on the development of knowledge regarding risk of cardiovascular disease in children, adolescents and young adults, and the clinical practice of pediatric prevention.

Features

• ISBN13: 9780195150650
• Condition: USED - Very Good
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